Ms Chan, 26 years old.  She has just married and preparing for Pregnancy. She has heard that her friends and couples are carriers of Alpha-thalassemia. The couple’s children are unfortunately inherited to Alpha-thalassemia.

Alpha-thalassemia is one of the common recessive genetic diseases, the carrier rate of thalassemia is high in the Asia population. The patients need to do blood transfusions in Life long, and even severe deaths in adolescence, therefore, Ms Chan is worried about her next child. 

She decided to conduct NJ20 carrier risk assessment Test.

Although the report showed that Ms Chan was not a carrier of Alpha-thalassemia, more important information found that one of the IDS genes had a mutation in the pathogenic gene. Therefore, she is a carrier of Mucopolysaccharidosis type II. If her partner is also a carrier of Mucopolysaccharidosis type II, there are 25% risk of their next generations is a severely patient with the Mucopolysaccharidosis type II. 

So her partner, Mr Cheung decided to conduct the test.  The report shows that Mr Cheung is a carrier of Alpha-thalassemia. According to the report, although their child is a serious patient with Alpha-thalassemia, however, there are also 1/2 chances of becoming a carrier of Mucopolysaccharidosis type II or a carrier of Alpha-thalassemia. A further 1/4 chance to become a carrier of both diseases and continues to affect the health of the next generation.